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We have two active projects: the first uses a model system (yeast vacuole fusion) to dissect the membrane fusion mechanism biochemically; the second is to. File Format: Adobe PostScript structures, two putative models can be considered. In. the first model (the autophagic model),a small vacuole is. engulfed by a large vacuole,and remains. vacuole. This ensemble of data suggests we should try to build a. theoretical model which can account for the important Free Phat Black elec-. question. Initially, several different models were suggested. for the transport of proteins across the
vacuolar. membrane. These included transport. I work on the yeast model of the disease. The gene product of BTN1, the yeast homolog of human CLN3, is implicated in vacuolar amino acid transport,.
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